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1

Mutagenesis studies of the human MT2 melatonin receptor

Matthew J Gerdin, Faika Mseeh, Margarita L Dubocovich

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

2

Identification of cysteines involved in ligand binding to the human melatonin MT2 receptor

Faika Mseeh, Matthew J. Gerdin, Margarita L. Dubocovich

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 3.90 MB

english, 2002

3

Crystal Structure of Human Riboflavin Kinase Reveals a β Barrel Fold and a Novel Active Site Arch

Subramanian Karthikeyan, Qingxian Zhou, Faika Mseeh, Nick V. Grishin, Andrei L. Osterman, Hong Zhang

Journal:

Year:

2003

Language:

english

File:

PDF, 656 KB

english, 2003

4

Lack of interaction of serotonin levels and bone mass in LRP5 and TPH1 knockout mice and following pharmacological reduction of intestinal serotonin content

R. Brommage, Q. Yang, J. Liu, F. Mseeh, W. Yu, S. Jeter-Jones, Z.-C. Shi, B. Zambrowicz, Q. Liu, D.R. Powell

Journal:

Year:

2011

Language:

english

File:

PDF, 62 KB

english, 2011

5

Inactivation of Platelet PDE2 by an Affinity Label: 8-[(4-Bromo-2,3-Dioxobutyl)Thio]cAMP

Faika Mseeh, Roberta F Colman, Robert W Colman

Journal:

Thrombosis Research

Year:

2000

Language:

english

File:

PDF, 92 KB

english, 2000

6

LX4211 Increases Serum Glucagon-Like Peptide 1 and Peptide YY Levels by Reducing Sodium/Glucose Cotransporter 1 (SGLT1)-Mediated Absorption of Intestinal Glucose

Powell, D. R., Smith, M., Greer, J., Harris, A., Zhao, S., DaCosta, C., Mseeh, F., Shadoan, M. K., Sands, A., Zambrowicz, B., Ding, Z.-M.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2013

Language:

english

File:

PDF, 546 KB

english, 2013

7

Identification of Small Molecules That Selectively Inhibit Diacylglycerol Lipase- Activity

Appiah, K. K., Blat, Y., Robertson, B. J., Pearce, B. C., Pedicord, D. L., Gentles, R. G., Yu, X.-C., Mseeh, F., Nguyen, N., Swaffield, J. C., Harden, D. G., Westphal, R. S., Banks, M. N., O'Connell,

Journal:

Journal of Biomolecular Screening

Year:

2014

Language:

english

File:

PDF, 988 KB

english, 2014

8

Effect of LX4211 on Glucose Homeostasis and Body Composition in Preclinical Models

Powell, D. R., DaCosta, C. M., Smith, M., Doree, D., Harris, A., Buhring, L., Heydorn, W., Nouraldeen, A., Xiong, W., Yalamanchili, P., Mseeh, F., Wilson, A., Shadoan, M., Zambrowicz, B., Ding, Z.-M.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2014

Language:

english

File:

PDF, 312 KB

english, 2014

9

From Genetic Footprinting to Antimicrobial Drug Targets: Examples in Cofactor Biosynthetic Pathways

Gerdes, S. Y., Scholle, M. D., D'Souza, M., Bernal, A., Baev, M. V., Farrell, M., Kurnasov, O. V., Daugherty, M. D., Mseeh, F., Polanuyer, B. M., Campbell, J. W., Anantha, S., Shatalin, K. Y., Chowdhu

Journal:

Journal of Bacteriology

Year:

2002

Language:

english

File:

PDF, 749 KB

english, 2002

10

Improved glycemic control in mice lacking Sglt1 and Sglt2

Powell, D. R., DaCosta, C. M., Gay, J., Ding, Z.-M., Smith, M., Greer, J., Doree, D., Jeter-Jones, S., Mseeh, F., Rodriguez, L. A., Harris, A., Buhring, L., Platt, K. A., Vogel, P., Brommage, R., Shad

Journal:

AJP Endocrinology and Metabolism

Year:

2013

Language:

english

File:

PDF, 2.80 MB

english, 2013

11

LX4211, a Dual SGLT1/SGLT2 Inhibitor, Improved Glycemic Control in Patients With Type 2 Diabetes in a Randomized, Placebo-Controlled Trial

Zambrowicz, B, Freiman, J, Brown, P M, Frazier, K S, Turnage, A, Bronner, J, Ruff, D, Shadoan, M, Banks, P, Mseeh, F, Rawlins, D B, Goodwin, N C, Mabon, R, Harrison, B A, Wilson, A, Sands, A, Powell,

Journal:

Clinical Pharmacology & Therapeutics

Year:

2012

Language:

english

File:

PDF, 564 KB

english, 2012

12

Identification of potent and selective MTH1 inhibitors

Petrocchi, Alessia, Leo, Elisabetta, Reyna, Naphtali J., Hamilton, Matthew M., Shi, Xi, Parker, Connor A., Mseeh, Faika, Bardenhagen, Jennifer P., Leonard, Paul, Cross, Jason B., Huang, Sha, Jiang, Yo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 2.07 MB

english, 2016

13

LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2

Powell, David R., Smith, Melinda G., Doree, Deon D., Harris, Angela L., Xiong, Wendy W., Mseeh, Faika, Wilson, Alan, Gopinathan, Suma, Diaz, Damaris, Goodwin, Nicole C., Harrison, Bryce, Strobel, Eric

Journal:

Pharmacology Research & Perspectives

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

14

Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes

Goodwin, Nicole C., Ding, Zhi-Ming, Harrison, Bryce A., Strobel, Eric D., Harris, Angela L., Smith, Melinda, Thompson, Andrea Y., Xiong, Wendy, Mseeh, Faika, Bruce, Debra J., Diaz, Damaris, Gopinathan

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.60 MB

english, 2017

15

Discovery of IACS-9439, a potent, exquisitely selective and orally bioavailable inhibitor of CSF1R

Czako, Barbara, Marszalek, Joseph R, Burke, Jason P, Mandal, Pijus K, Leonard, Paul G., Cross, Jason B, Mseeh, Faika, Jiang, Yongying, Chang, Edward Q, Suzuki, Erika, Jeffrey, Kovacs J, Feng, Ningping

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.38 MB

2020

16

Allosteric SHP2 inhibitor IACS-13909 overcomes EGFR-dependent and EGFR-independent resistance mechanisms towards osimertinib

Sun, Yuting, Meyers, Brooke A., Czako, Barbara, Leonard, Paul, Mseeh, Faika, Harris, Angela L., Wu, Qi, Johnson, Sarah, Parker, Connor A., Cross, Jason B., Di Francesco, Maria Emilia, Bivona, Benjamin

Journal:

Cancer Research

Year:

2020

File:

PDF, 8.01 MB

2020